Abstract: Objective To analyze the relationship between basic diseases and prognosis in patients with pyogenic liver abscess (PLA).Methods One hundred and fifty-three patients with PLA admitted to the NO.988 Hospital of Joint Logistic Support Force from January 2015 to January 2020 were selected as the research objects. According to the associated basic diseases, they were divided into group A (diabetes group), group B (biliary group), group C (diabetes + biliary group) and group D (other factors) for retrospective study to understand the correlation between them and prognosis. Results Klebsiella pneumoniae and Gram-positive bacteria were the main pathogens in group A and group D, the focus was single and the prognosis was better; group B and group C were mainly E.coli due to biliary factors, the focus was often multiple and the prognosis was poor, the difference was statistically significant (P<0.05).Conclusion When PLA occurs, it is helpful to know the state of basic diseases in detail, to make treatment plan and to judge prognosis.

Key words: Pyogenic liver abscess, Basic disease, Diabetes mellitus, Biliary disease, Prognosis correlation