Abstract: Objective To observe the effect of ultrasound combined with multi-slice spiral CT-guided puncture-aspiration or catheter drainage on inflammatory response in patients with bacterial liver abscess. Methods 84 patients with bacterial liver abscess who admitted in the hospital from February 2017 to August 2019 were selected as subjects. All patients underwent ultrasound combined with multi-slice spiral CT-guided surgery, and they were divided into aspiration group and catheter drainage group according to the treatment methods, with 42 cases in each group. The curative effects of two groups were evaluated and compared. On admission, after the 3^rd and 7^rd day after surgery, the peripheral elbow venous blood of patients was collected, and the inflammatory response indexes [procalcitonin (PCT), C-reactive protein (CRP)] were detected after processing. The postoperative complications in each group were recorded. Results The results of rank sum test of ranked data showed that there was no statistical difference in the overall curative effects between aspiration group and catheter drainage group (P>0.05). The results of chi-square test showed that there was no statistical difference in the total effective rate between the two groups (P>0.05). After surgery for 3 d and 7 d, the levels of PCT and CRP in two groups were lower than those on admission (P<0.05). There was no statistical difference in the levels of PCT and CRP between two groups at each time after surgery (P>0.05). There were no severe postoperative complications in both groups. Conclusion After clarifying the indications for patients with bacterial liver abscess, ultrasound combined with multi-slice spiral CT-guided puncture drainage or aspiration therapy could alleviate inflammatory response and achieve better drainage effects, and have no complications, which was safe and reliable.

Key words: Bacterial liver abscess, Puncture drainage, Ultrasound, Multi-slice spiral CT, Inflammatory response