[1] Milane L, Singh A, Mattheolabakis G, et al. Exosome mediated communication within the tumor microenvironment. J Control Release,2015, 219: 278-294. [2] Chen F, Wang N, Tan H Y, et al. The functional roles of exosomes-derived long non-coding RNA in human cancer. Cancer Biol Ther,2019, 20: 583-592. [3] Sohn W, Kim J, Kang S H, et al. Serum exosomal microRNAs as novel biomarkers for hepatocellular carcinoma. Exp Mol Med,2015, 47: e184. [4] Wang H, Hou L, Li A, et al. Expression of serum exosomal microRNA-21 in human hepatocellular carcinoma. Biomed Res Int,2014, 2014: 864894. [5] Liu W H, Ren L N, Wang X, et al. Combination of exosomes and circulating microRNAs may serve as a promising tumor marker complementary to alpha-fetoprotein for early-stage hepatocellular carcinoma diagnosis in rats. J Cancer Res Clin Oncol,2015, 141: 1767-1778. [6] Wu X, Wu S, Tong L, et al. miR-122 affects the viability and apoptosis of hepatocellular carcinoma cells. Scand J Gastroenterol,2009, 44: 1332-1339. [7] Sugimachi K, Matsumura T, Hirata H, et al. Identification of a bona fide microRNA biomarker in serum exosomes that predicts hepatocellular carcinoma recurrence after liver transplantation. Br J Cancer,2015, 112: 532-538. [8] Liu W, Hu J, Zhou K, et al. Serum exosomal miR-125b is a novel prognostic marker for hepatocellular carcinoma. Onco Targets Ther,2017, 10: 3843-3851. [9] Ahmed E K, Fahmy S A, Effat H, et al. Circulating MiR-210 and MiR-1246 as potential biomarkers for differentiating hepatocellular carcinoma from metastatic tumors in the liver. J Med Biochem,2019, 38:109-117. [10] Conde-Vancells J, Rodriguez-Suarez E, Gonzalez E, et al. Candidate biomarkers in exosome-like vesicles purified from rat and mouse urine samples. Proteomics Clin Appl,2010, 4:416-425. [11] Cho Y E, Kim S H, Lee B H, et al. Circulating plasma and exosomal microRNAs as indicators of drug-induced organ injury in rodent models. Biomol Ther (Seoul),2017, 25: 367-373. [12] Zheng J, Yu L, Chen W, et al. Circulating exosomal microRNAs reveal the mechanism of Fructus Meliae Toosendan-induced liver injury in mice. Sci Rep,2018, 8: 2832. [13] Verma VK, Li H, Wang R, et al. Alcohol stimulates macrophage activation through caspase-dependent hepatocyte derived release of CD40L containing extracellular vesicles. J Hepatol,2016, 64: 651-660. [14] Momen-Heravi F, Saha B, Kodys K, et al. Increased number of circulating exosomes and their microRNA cargos are potential novel biomarkers in alcoholic hepatitis. J Transl Med,2015, 13: 261. [15] Babuta M, Furi I, Bala S, et al. Dysregulated autophagy and lysosome function are linked to exosome production by Micro-RNA 155 in alcoholic liver disease. Hepatology,2019, 70: 2123-2141. [16] Lee YS, Kim SY, Ko E, et al. Exosomes derived from palmitic acid-treated hepatocytes induce fibrotic activation of hepatic stellate cells. Sci Rep,2017, 7: 3710. [17] Ibrahim SH, Hirsova P, Tomita K, et al. Mixed lineage kinase 3 mediates release of C-X-C motif ligand 10-bearing chemotactic extracellular vesicles from lipotoxic hepatocytes. Hepatology,2016, 63: 731-744. [18] Kakazu E, Mauer AS, Yin M, et al. Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner. J Lipid Res,2016, 57: 233-245. [19] Bukong TN, Momen-Heravi F, Kodys K, et al. Exosomes from hepatitis C infected patients transmit HCV infection and contain replication competent viral RNA in complex with Ago2-miR122-HSP90. PLoS Pathog,2014, 10: e1004424. [20] Welker MW, Reichert D, Susser S, et al. Soluble serum CD81 is elevated in patients with chronic hepatitis C and correlates with alanine aminotransferase serum activity. PLoS One,2012, 7: e30796. [21] Zhao X, Wu Y, Duan J, et al. Quantitative proteomic analysis of exosome protein content changes induced by hepatitis B virus in Huh-7 cells using SILAC labeling and LC-MS/MS. J Proteome Res,2014, 13: 5391-5402. [22] Chen L, Charrier A, Zhou Y, et al. Epigenetic regulation of connective tissue growth factor by MicroRNA-214 delivery in exosomes from mouse or human hepatic stellate cells. Hepatology,2014, 59: 1118-1129. [23] Chen L, Chen R, Velazquez VM, et al. Fibrogenic signaling is suppressed in hepatic stellate cells through targeting of connective tissue growth factor (CCN2) by cellular or exosomal MicroRNA-199a-5p. Am J Pathol,2016, 186: 2921-2933. [24] Wang R, Ding Q, Yaqoob U, et al. Exosome adherence and internalization by hepatic stellate cells triggers sphingosine 1-Phosphate-dependent migration. J Biol Chem,2015, 290: 30684-30696. [25] Momen-Heravi F, Bala S, Kodys K, et al. Exosomes derived from alcohol-treated hepatocytes horizontally transfer liver specific miRNA-122 and sensitize monocytes to LPS. Sci Rep,2015, 5: 9991. [26] Jiang PY, Zhu XJ, Jiang RA, et al. MicroRNAs derived from urinary exosomes act as novel biomarkers in the diagnosis of intrahepatic cholestasis of pregnancy. Am J Transl Res,2019, 11: 6249-6261. [27] Zou P, Luo L, Zhao C, et al. The serum microRNA profile of intrahepatic cholestasis of pregnancy: identification of novel noninvasive biomarkers. Cell Physiol Biochem,2018, 51: 1480-1488. [28] Zhang X, Yu L, Ding Y. Human leukocyte antigen G and miR-148a are associated with the pathogenesis of intrahepatic cholestasis of pregnancy. Exp Ther Med,2014, 8: 1701-1706. [29] Rao ZZ, Zhang XW, Ding YL, et al. miR-148a-mediated estrogen-induced cholestasis in intrahepatic cholestasis of pregnancy: Role of PXR/MRP3. PLoS One,2017, 12: e0178702. [30] Ma L, Zhang XQ, Zhou DX, et al. Feasibility of urinary microRNA profiling detection in intrahepatic cholestasis of pregnancy and its potential as a non-invasive biomarker. Sci Rep,2016, 6: 31535. |