Abstract: Objective To investigate the etiology and clinical characteristics of neonatal jaundice.Methods The clinical data of 431 neonates with jaundice in our hospital were analyzed, and the clinical etiology, high risk factors and the clinical characteristics of the condition of jaundice were analyzed statistically by comparing the correlation of the risk factors.Results There were 172 infectious cases (39.91%) , 84 hemolysis cases (19.49%), 49 cases with perinatal hypoxia and scalp hematoma (11.37%), 22 delayed defecation cases (5.10%), 4 cases with polycythemia (0.70%), and 73 cases with unknown jaundice (16.94%). Among the high risk factors, there were 80 neonatus whose mother with gestational diabetes (18.56%), 45 whose mother with hypothyroidism (10.44%), 34 with neonatal hypoproteinemia (7.89%), and 17 with neonatal hypoglycemia (3.94%). There was no significant deference in transaminase between the infection group and the non-infection group.Conclusion Infection, hemolysis and perinatal factors are the main causes of neonatal jaundice in our hospital.

Key words: Neonate jaundice, Pathogenesis, Transaminase