Abstract: Objective To observe the electrocardiograph (ECG) and echocardiographic features of patients, with hepatitis B virus (HBV) -related cirrhosis and to evaluate the heart involvement.Methods A total of 50 patients with HBV-related cirrhosis admitted to our hospital from July 1, 2019 to November 30, 2020 were enrolled as the study group. A total of 41 hepatitis B patients hospitalized at the same period were selected as the control group. All the subjects underwent ECG and echocardiography, and then the differences of cardiac?electrophysiology [heart rate (HR), P wave, PR interval, QRS wave, QTc], cardiac?structure [left atrium (LA), right ventricular (RV), main pulmonary artery (MPA), left ventricular end diastolic diameter (LVDd), left ventricular end systolic diameter (LVDs), aortic root (AOR), aorta ascendens (AO)] and cardiac?function [left ventricular ejection fraction (LVEF), E, A, E/A, pulmonary blood flow velocity (PV), aortic blood flow velocity (AV)] between the 2 groups were compared.Results The QTc interval of study group was (443.6 ± 26.6)ms, which was significantly higher than that of control group [(426.1 ± 20.8)ms, t=-3.444, P<0.001]. The LA of study group was (35.8 ± 4.3) mm, which was significantly higher than that of control group [(32.5 ± 4.7) mm, t=-3.509, P<0.001]. The PV of study group was (105.9 ± 31.8)cm/s, which was higher than that of control group [(92.2 ± 18.7)cm/s, t=-2.427, P<0.05]. There was no significant difference on other indexes (HR, P wave, PR interval, QRS wave, RV, MPA, LVDd, LVDs, AOR, AO, LVEF, E, A, E/A, AV).Conclusion Abnormality of cardiac electrophysiology, structure and function including prolonged QTc, enlarged LA and increased PV might occur in patients with HBV-related cirrhosis.

Key words: Cirrhosis, Hepatitis B, Echocardiography, Electrocardiograph