Abstract: Objective To investigate the clinical features and summarize the key aspects of diagnosis and treatment in diabetic patients with invasive Klebsiella pneumoniae liver abscess syndrome. Methods From 2017 to 2023, 17 diabetic patients with liver abscess syndrome were selected. All patients exhibited elevated inflammatory markers, abnormal lung imaging, poor blood glucose control, and Klebsiella pneumoniae was identified in pus or blood culture. Prognosis improved through monitoring vital signs, liver abscess puncture and drainage, antibiotic therapy, blood glucose control, and nutritional support. Results In diabetic patients with invasive Klebsiella pneumoniae liver abscess syndrome, comprehensive treatment-including liver abscess puncture and drainage, blood glucose control, and appropriate antibiotic therapy-resulted in normalization of inflammatory markers, effective blood glucose management, absence of postoperative complications , and no detection of pathogenic bacteria in blood culture. Conclusion In the treatment of diabetic patients with invasive Klebsiella pneumoniae liver abscess syndrome, rigorous clinical standards should be established for blood glucose monitoring, liver abscess puncture and drainage, rational antibiotic use, nutritional support, and daily care.

Key words: Liver abscess, Klebsiella pneumoniae, Diabetes